Join Our Mailing List Today!

NOTICE: Website will be down 1/28–1/29. Online ordering will be disabled 1/27-1/31. Learn More.

PRIME-XV T Cell CDM

In stock
Catalog ID
91154

Offering the ability to scale-up to various automated bioreactors with increased speed for T cell culture, PRIME-XV T Cell CDM is fully optimized for immune therapy and research. Chemically-defined and animal component-free, it delivers consistent growth while maintaining T cell functionality and potency in scalable therapy or research.</p>

Size Stock SKU Unit Price Qty
1 L In Stock 91154-1L
$337.00
reset
Details

PRIME-XV T Cell CDM is the first commercially available chemically-defined, animal component-free medium for the expansion and cultivation of human T cells. The performance and functionality of PRIME-XV T Cell CDM continues to set the standard as the application process becomes more dynamic and closed.

Provides optimal performance:

  • Supports vigorous T cell growth in static and dynamic automation systems while maintaining functionality
  • Provides lot-to-lot consistency for reliable formulation composition
  • Removes the effects of undefined components to minimize unwarranted T cell phenotypes
  • Supports polarization to targeted T cell types such as Th1 and T regulatory cells to further possible therapy applications

Manufactured to facilitate transfer from research to clinic:

  • Chemically-defined, animal component-free formula minimizes risks from adventitious agents
  • Manufactured in compliance with cGMP regulations
  • Traceability documentation provided including Certificates of Analysis, Certificates of Origin, and a Drug Master File (DMF) filed with the US FDA
  • Extensive QA testing including functionality, sterility, and endotoxin
  • Custom formulation, sizes and packaging available for all commercially available automation systems

PRIME-XV T Cell CDM supports viable T cell expansion across different culture vessels

Figure 1: (A) Fold expansion of CD3+ cells in PRIME-XV T Cell CDM is robust across the three documented culture systems, performing as well as or better than FBS-supplemented RPMI and commercially available XSF media. (B) Viability is maintained at or above 85% by the end of the culture period in all three cell culture systems. Though significant inter-donor variability is observed, these data are representative of three donors, analyzed on day 14 (plates, flasks and G-Rex) or day 9 (Quantum bioreactors).

Publication, presentation, and protocol available for download

  • Protocols support G-Rex and Quantum
  • Protocols for plates and flasks can be provided upon request

Specifications

Storage
This product is shipped at 2-8°C with cold packs. Upon receipt, store immediately at 2-8°C and protect from light.
Shelf Life
Handle using aseptic techniques to avoid contamination. Unopened liquid medium is stable for 14 months from date of manufacture, as indicated on the label.
© 2022 FUJIFILM Irvine Scientific. All rights reserved.