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Catalog ID

Chemically defined, animal component-free medium for natural killer (NK) and NKT cell expansion optimized to deliver cell growth while maintaining NK and NKT cell functionality and potency.

Size Stock SKU Unit Price Qty
1 L Inquire for Availability 91215-1L

    PRIME-XV NK Cell CDM is the first commercially-available, chemically defined, and animal component-free medium for the ex vivo expansion of NK and NKT cells.

    Designed for use in NK and NKT cell-based immunotherapy research and translational applications, this advanced formulation delivers growth while maintaining NK and NKT cell functionality and potency - without the need for serum supplementation.

    Provides Optimal Performance

    Chemically defined, animal component-free natural killer cell culture medium

    • Supports robust cell expansion and viability in heterogeneous PBMC culture enriched for CD56+ cells
    • Supports expansion of NK cells when supplemented with IL-2, IL-12, IL-18, and IL-21
    • Supports NKT cell expansion when supplemented with IL-2
    • Maintains high NK and NKT cytotoxic capability

    Designed and manufactured to facilitate transfer from research to clinic. Supported by robust raw material controls and supply chain management  

    • FDA, Federal, and State registered - cGMP-compliant manufacture
    • EN ISO 13485:2016 certified
    • MDSAP certified
    • Extensive QC testing including functionality, sterility (USP <71>), endotoxin (USP <85>), and mycoplasma (USP <63>)
    • Drug Master Files (DMFs) filed with the FDA – available upon request

    Custom sizes and packaging available upon request.

    Contact us for international pricing and custom formulations.

    Improved NK Cell Expansion in Chemically-defined Conditions


    This product is shipped at 2-8°C with cold packs. Upon receipt, store immediately at 2-8°C and protect from light.
    Shelf Life
    Unopened liquid medium is stable for 18 months from date of manufacture, as indicated on the label, when stored at 2-8°C and protected from light. Once opened, the product should be stored at 2-8°C in the dark and used within 4 weeks.
    Product Inserts
    Product Sheets
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