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Recombinant Rat Leptin

In stock
Catalog ID
300-14
Size Stock SKU Unit Price Qty
200 µg Inquire for Availability 300-14-200UG
$73.00
    1 mg In Stock 300-14-1MG
    $183.00
      5 mg In Stock 300-14-5MG
      $517.00
        10 mg In Stock 300-14-10MG
        $931.00
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          Details

          Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

          Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

          Instructions

          Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

          Technical Specifications

          Alternate Names Obesity protein
          Accession Number P50596
          Source Genetically modified E.coli
          Predicted Molecular Mass Monomer, 16.3 kDa (147 aa)
          AA Sequence MVPIHKVQDD TKTLIKTIVT RINDISHTQS VSARQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQILTSLP SQNVLQIAHD LENLRDLLHL LAFSKSCSLP QTRGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDLSPEC
          Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
          Product Reconstitution Sterile water at 0.1 mg/mL
          Country of Origin USA

           

          Specification* Method of Determination Acceptance Criteria
          Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
          Endotoxin Kinetic LAL ≤ 1 EU/µg
          Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

           

          *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

          Specifications

          Storage
          At or below -20°C
          Shelf Life
          12 months from date of receipt when stored at -20°C to-80°C as supplied.
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