Recombinant Rat IL-6

In stock

Catalog ID

300-09

Size	Stock	SKU	Unit Price
10 µg	Inquire for Availability	300-09-10UG	$183.00
100 µg	In Stock	300-09-100UG	$705.00
500 µg	Inquire for Availability	300-09-500UG	$3,503.00
1 mg	Inquire for Availability	300-09-1MG	$5,839.00
10 µg (Animal-Free)	In Stock	300-09AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	300-09AF-100UG	$773.00
500 µg (Animal-Free)	Inquire for Availability	300-09AF-500UG	$3,857.00
1 mg (Animal-Free)	Inquire for Availability	300-09AF-1MG	$6,422.00

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Details

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	IFN-β2, B-cell Differentiation Factor, BSF-2, HSF, MGI-2
Accession Number	P20607
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 21.9 kDa (188 aa)
AA Sequence	MFPTSQVRRG DFTEDTTHNR PVYTTSQVGG LITYVLREIL EMRKELCNGN SDCMNSDDAL SENNLKLPEI QRNDGCFQTG YNQEICLLKI CSGLLEFRFY LEFVKNNLQD NKKDKARVIQ SNTETLVHIF KQEIKDSYKI VLPTPTSNAL LMEKLESQKE WLRTKTIQLI LKALEEFLKV TMRSTRQT
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) + 2:1 mannitol to protein
Product Reconstitution	Sterile 10 mM HCl at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 90%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	B9 cell proliferation	≤ 2 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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