Recombinant Rat IFN-γ

In stock

Catalog ID

300-04

Size	Stock	SKU	Unit Price
20 µg	Inquire for Availability	300-04-20UG	$73.00
100 µg	In Stock	300-04-100UG	$183.00
250 µg	In Stock	300-04-250UG	$419.00
500 µg	Inquire for Availability	300-04-500UG	$700.00
1 mg	In Stock	300-04-1MG	$1,217.00

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Details

Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation. IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. If a precipitate is observed, centrifuge the solution thoroughly and use only the soluble fraction (removing it from the precipitate). A 10% overfill has been added to compensate for any loss of protein in the precipitate. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	Type II interferon, T cell interferon, Immune Interferon, MAF
Accession Number	P01581
Source	Genetically modified E.coli
Predicted Molecular Mass	Noncovalently-linked homodimer, 15.6 / 31.2 kDa (135 / 270 aa)
AA Sequence	MQGTLIESLE SLKNYFNSSS MDAMEGKSLL LDIWRNWQKD GNTKILESQI ISFYLRLFEV LKDNQAISNN ISVIESHLIT NFFSNSKAKK DAFMSIAKFE VNNPQIQHKA VNELIRVIHQ LSPESSLRKR KRSRC
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, 100 mM sodium chloride, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	No biological activity data is available at this time	No biological activity data is available at this time

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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