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Recombinant Human PDGF-BB

In stock
Catalog ID
Size Stock SKU Unit Price Qty
10 µg In Stock 100-18-10UG
    100 µg In Stock 100-18-100UG
      500 µg In Stock 100-18-500UG
        1 mg In Stock 100-18-1MG
          10 µg (Animal-Free) In Stock 100-18AF-10UG
            100 µg (Animal-Free) In Stock 100-18AF-100UG
              500 µg (Animal-Free) In Stock 100-18AF-500UG
                1 mg (Animal-Free) In Stock 100-18AF-1MG

                  Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.


                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names GDGF, ODGF
                  Accession Number P01127
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Dimer, 12.4/24.9 kDa (110/220 aa)
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
                  Product Reconstitution Sterile water at 0.1 mg/mL
                  Country of Origin USA


                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                  Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                  Biological Activity (ED50) NR6R-3T3 cell proliferation ≤ 20 ng/mL; ≥ 5.0 x 104 units/mg


                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.


                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to -80°C as supplied.
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