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Recombinant Human Fractalkine / CX3CL1

In stock
Catalog ID
100-174
Size Stock SKU Unit Price Qty
5 µg Inquire for Availability 100-174-5UG
$73.00
    20 µg In Stock 100-174-20UG
    $183.00
      100 µg In Stock 100-174-100UG
      $457.00
        500 µg Inquire for Availability 100-174-500UG
        $1,971.00
          1 mg Inquire for Availability 100-174-1MG
          $3,284.00
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            Details

            Fractalkine, also known as CX3CL1, is a cytokine protein containing a CX3C chemokine motif atop a mucin stalk. Fractalkine is produced by non-hemopoietic cells, including neurons and astrocytes. Soluble fractalkine functions as a chemoattractant for T cells and monocytes. Cell-membrane-bound fractalkine, which is induced on activated endothelial cells, promotes leukocyte adhesion. The transmembrane chemokine receptor CX3CR1 mediates the adhesive and chemoattractant functions of fractalkine.

            Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

            Instructions

            Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

            Technical Specifications

            Alternate Names Neurotactin
            Accession Number P78423
            Source Genetically modified E.coli
            Predicted Molecular Mass Monomer, 8.6 kDa (76 aa)
            AA Sequence QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG
            Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
            Product Reconstitution Sterile water at 0.1 mg/mL
            Country of Origin USA

             

            Specification* Method of Determination Acceptance Criteria
            Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
            Endotoxin Kinetic LAL ≤ 0.1 EU/µg
            Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

             

            *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

            Specifications

            Storage
            At or below -20°C
            Shelf Life
            12 months from date of receipt when stored at -20°C to-80°C as supplied.
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