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Recombinant Mouse p28 subunit (IL-27)

In stock
Catalog ID
200-50
Size Stock SKU Unit Price Qty
10 µg In Stock 200-50-10UG
$183.00
    100 µg In Stock 200-50-100UG
    $705.00
      500 µg Inquire for Availability 200-50-500UG
      $3,503.00
        1 mg Inquire for Availability 200-50-1MG
        $5,839.00
          10 µg (Animal-Free) Inquire for Availability 200-50AF-10UG
          $200.00
            100 µg (Animal-Free) Inquire for Availability 200-50AF-100UG
            $773.00
              500 µg (Animal-Free) Inquire for Availability 200-50AF-500UG
              $3,857.00
                1 mg (Animal-Free) Inquire for Availability 200-50AF-1MG
                $6,422.00
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                  Details

                  The p28 subunit of interleukin 27 (IL-27), also known as interleukin 30 (IL-30), is a member of the interleukin 12 (IL-12) family of cytokines. p28 is a secreted polypeptide that associates with the Epstein-Barr virus induced gene 3 (EBI3) to form the IL-27 cytokine heterodimer complex. IL-27 functions as a proinflammatory cytokine that induces immunomodulatory effects in naïve CD4+ T cells, mast cells, and monocytes. p28 can also form a complex with cytokine-like factor 1 (CLF), that is secreted by dendritic cells, to regulate natural killer (NK) and T cell functions. 

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                  Instructions

                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names IL-30, P28, IL-27 p28 subunit
                  Accession Number Q8K3I6
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Monomer, 23.7 kDa (207 aa)
                  AA Sequence MFPTDPLSLQ ELRREFTVSL YLARKLLSEV QGYVHSFAES RLPGVNLDLL PLGYHLPNVS LTFQAWHHLS DSERLCFLAT TLRPFPAMLG GLGTQGTWTS SEREQLWAMR LDLRDLHRHL RFQVLAAGFK CSKEEEDKEE EEEEEEEEKK LPLGALGGPN QVSSQVSWPQ LLYTYQLLHS LELVLSRAVR DLLLLSLPRR PGSAWDS
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium bicarbonate, pH 8.5
                  Product Reconstitution Sterile water at 0.1 mg/mL
                  Country of Origin USA

                   

                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                  Endotoxin Kinetic LAL ≤ 1 EU/µg
                  Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

                   

                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                  Specifications

                  Storage
                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to-80°C as supplied.
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