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Recombinant Mouse IL-4

In stock
Catalog ID
200-18
Size Stock SKU Unit Price Qty
5 µg In Stock 200-18-5UG
$73.00
5 µg (Animal-Free) In Stock 200-18AF-5UG
$79.00
20 µg In Stock 200-18-20UG
$183.00
20 µg (Animal-Free) In Stock 200-18AF-20UG
$200.00
100 µg In Stock 200-18-100UG
$475.00
100 µg (Animal-Free) In Stock 200-18AF-100UG
$504.00
500 µg In Stock 200-18-500UG
$2,335.00
500 µg (Animal-Free) Inquire for Availability 200-18AF-500UG
$2,481.00
1 mg In Stock 200-18-1MG
$3,893.00
1 mg (Animal-Free) Inquire for Availability 200-18AF-1MG
$4,135.00
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Details

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names B cell Stimulating Factor, BSF-1, BCDF, BCGF
Accession Number P07750
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 13.7 kDa (121 aa)
AA Sequence MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDY S
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) HT-2 proliferation ≤ 20 ng/mL; ≥ 5.0 x 104 units/mg

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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