Recombinant Mouse IL-13

In stock

Catalog ID

200-22

Size	Stock	SKU	Unit Price
10 µg	In Stock	200-22-10UG	$183.00
100 µg	In Stock	200-22-100UG	$705.00
500 µg	Inquire for Availability	200-22-500UG	$3,503.00
1 mg	Inquire for Availability	200-22-1MG	$5,839.00

Find Your Distributor

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Details

Interleukin 13 (IL-13) is a cytokine secreted from type 2 T helper (Th2) cells. IL-13 has overlapping functions with interleukin 4 (IL-4), including the induction of immunoglobulin E (IgE) secretion from B cells, and the inhibition of interleukin 1 beta (IL-1β), tumor necrosis factor alpha (TNF-α), interleukin 8 (IL-8), and interleukin 6 (IL-6) inflammatory cytokine expression. IL-13 also regulates immune cell inflammation in response to the pathophysiological changes of surrounding non-immune cells. The IL-13 receptor consists of the IL-4Ra and IL-13Ra1 subunits. IL-13 can also bind the IL-13Ra2 receptor with high affinity. IL-13 functions are mediated through the JAK/STAT signaling pathway. Human and mouse IL-13 are cross-reactive.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	NC30
Accession Number	P20109
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 12.3 kDa (111 aa)
AA Sequence	MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
Formulation	Lyophilized from a 0.2 filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile 20 mM HCl at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	TF-1 cell proliferation	≤ 10 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

COA Search

Certificates of Analysis Search