Recombinant Mouse FLT-3 Ligand

In stock

Catalog ID

200-06

Size	Stock	SKU	Unit Price
10 µg	Inquire for Availability	200-06-10UG	$183.00
100 µg	Inquire for Availability	200-06-100UG	$529.00
500 µg	Inquire for Availability	200-06-500UG	$2,627.00
1 mg	Inquire for Availability	200-06-1MG	$4,379.00
10 µg (Animal-Free)	In Stock	200-06AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	200-06AF-100UG	$584.00
500 µg (Animal-Free)	Inquire for Availability	200-06AF-500UG	$2,889.00
1 mg (Animal-Free)	Inquire for Availability	200-06AF-1MG	$4,817.00

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Details

Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7,) or in combination of IL-7 and interleukin 3 (IL-3).

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	Flt3L, Fms-related tyrosine kinase 3 ligand
Accession Number	P49772
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 18.6 kDa (163 aa)
AA Sequence	MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	OCI-AML5 cell proliferation	≤ 10 ng/mL; ≥ 1.0 x 10⁵ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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