Join Our Mailing List Today!

NOTICE: Online ordering will be disabled 1/27-2/3. Learn More.

Recombinant Human OSM

In stock
Catalog ID
100-56
Size Stock SKU Unit Price Qty
10 µg In Stock 100-56-10UG
$183.00
    100 µg Inquire for Availability 100-56-100UG
    $705.00
      500 µg Inquire for Availability 100-56-500UG
      $3,503.00
        1 mg Inquire for Availability 100-56-1MG
        $5,839.00
          10 µg (Animal-Free) In Stock 100-56AF-10UG
          $200.00
            100 µg (Animal-Free) In Stock 100-56AF-100UG
            $773.00
              500 µg (Animal-Free) Inquire for Availability 100-56AF-500UG
              $3,857.00
                1 mg (Animal-Free) Inquire for Availability 100-56AF-1MG
                $6,422.00
                  reset
                  Details

                  Oncostatin M is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. The Type-I and Type-II Oncostatin M receptors are located on the cell surface of endothelial and tumor cells, contain the glycoprotein 130 (gp130) subunit, and activate the JAK/STAT signaling pathway. Oncostatin M functions to inhibit tumor cell proliferation, induce liver stem cell maturation, regulate cytokine production during hematopoiesis and inflammation, stimulate bone formation, and promote nervous system development.

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                  Instructions

                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names Onc-M
                  Accession Number P13725
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Monomer, 23.8 kDa (210 aa)
                  AA Sequence MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLGCVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRFLHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
                  Product Reconstitution Sterile water at 0.1 mg/mL
                  Country of Origin USA

                   

                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                  Endotoxin Kinetic LAL ≤ 1 EU/µg
                  Biological Activity (ED50) TF-1 cell proliferation ≤ 4 ng/mL

                   

                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                  Specifications

                  Storage
                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to-80°C as supplied.
                  © 2024 FUJIFILM Irvine Scientific. All rights reserved.