Recombinant Human NRG1-β

In stock

Catalog ID

100-46

Size	Stock	SKU	Unit Price
10 µg	In Stock	100-46-10UG	$73.00
50 µg	In Stock	100-46-50UG	$183.00
100 µg	In Stock	100-46-100UG	$330.00
500 µg	In Stock	100-46-500UG	$839.00
1 mg	In Stock	100-46-1MG	$1,460.00
10 µg (Animal-Free)	In Stock	100-46AF-10UG	$79.00
50 µg (Animal-Free)	In Stock	100-46AF-50UG	$200.00
100 µg (Animal-Free)	In Stock	100-46AF-100UG	$359.00
500 µg (Animal-Free)	Inquire for Availability	100-46AF-500UG	$948.00
1 mg (Animal-Free)	In Stock	100-46AF-1MG	$1,607.00

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Details

Neuregulin 1-beta (NRG1-β) is one of many alternatively-spliced isoforms of the NRG1 gene and contains a soluble EGF-like domain. The EGF-like domain of NRG1-β signals through the ErbB2, ErbB3, and ErbB4 receptor tyrosine kinases. NRG1-β is an important growth factor involved in neuroinflammation, nerve regeneration, and cardiovascular processes.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	NGR beta 1, neuregulin, HRG1 beta
Accession Number	Q02297-6
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 7.6 kDa (66 aa)
AA Sequence	MSHLVKCAEK EKTFCVNGGE CFMVKDLSNP SRYLCKCPNE FTGDRCQNYV MASFYKHLGI EFMEAE
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	Proliferation of MCF-7 cells	≤ 0.3 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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