Recombinant Human / Mouse TGF-β 3

In stock

Catalog ID

800-11

Size	Stock	SKU	Unit Price
10 µg	In Stock	800-11-10UG	$183.00
100 µg	In Stock	800-11-100UG	$711.00
500 µg	Inquire for Availability	800-11-500UG	$3,503.00
1 mg	Inquire for Availability	800-11-1MG	$5,839.00
10 µg (Animal-Free)	In Stock	800-11AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	800-11AF-100UG	$784.00
500 µg (Animal-Free)	Inquire for Availability	800-11AF-500UG	$3,857.00
1 mg (Animal-Free)	Inquire for Availability	800-11AF-1MG	$6,422.00

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Details

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution.

Technical Specifications

Alternate Names	None
Accession Number	P10600/P17125
Source	Genetically modified E.coli
Predicted Molecular Mass	Dimer, 12.9/25.7 kDa (113/226 aa)
AA Sequence	MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	Inhibition of IL-4-induced HT-2 cell proliferation	≤ 1 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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