Recombinant Human MIP-4 / CCL18

In stock

Catalog ID

100-136

Size	Stock	SKU	Unit Price
10 µg	In Stock	100-136-10UG	$183.00
100 µg	In Stock	100-136-100UG	$457.00
500 µg	Inquire for Availability	100-136-500UG	$1,971.00
1 mg	Inquire for Availability	100-136-1MG	$3,284.00

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Details

Macrophage inflammatory protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta, and bone marrow. MIP-4 receptors include the chemokine receptor 8 (CCR8), the G protein-coupled receptor 30 (GPR30), and the phosphatidylinositol transfer protein membrane-associate 3 (PITPNM3). MIP-4 acts as a chemoattractant for naive T cells, CD4+ T cells, CD8+ T cells, and nonactivated lymphocytes. Further, MIP-4 promotes breast cancer metastasis and attenuates the activation of acute lymphocytic leukemia B cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	CCL18, PARC, AMAC-1, DC-CK1
Accession Number	P55774
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 7.9 kDa (69 aa)
AA Sequence	AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	No biological activity data is available at this time	No biological activity data is available at this time

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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