Recombinant Human IL-4

In stock

Catalog ID

100-09

Size	Stock	SKU	Unit Price
5 µg	In Stock	100-09-5UG	$73.00
20 µg	In Stock	100-09-20UG	$183.00
100 µg	In Stock	100-09-100UG	$475.00
500 µg	In Stock	100-09-500UG	$2,335.00
1 mg	In Stock	100-09-1MG	$3,893.00
5 µg (Animal-Free)	Inquire for Availability	100-09AF-5UG	$79.00
20 µg (Animal-Free)	In Stock	100-09AF-20UG	$200.00
100 µg (Animal-Free)	In Stock	100-09AF-100UG	$504.00
500 µg (Animal-Free)	Inquire for Availability	100-09AF-500UG	$2,481.00
1 mg (Animal-Free)	In Stock	100-09AF-1MG	$4,135.00

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Details

Interleukin 4 (IL-4) is an immunomodulatory cytokine that functions to induce naïve helper T cells to differentiate into type 2 T helper (Th2) cells. Th2 cells subsequently produce more IL-4 in a positive feedback loop. IL-4 also promotes immunoglobulin IgG to IgE isotype switching on B cells. IL-4 binds the IL-4Rα receptor to activate STAT6 signaling.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	B-cell stimulatory factor-1, BSF-1, BCDF, BCGF
Accession Number	P05112
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 15.1 kDa (130 aa)
AA Sequence	MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	TF-1 cell proliferation	≤ 0.25 ng/mL; ≥ 4.0 x 10⁶ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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