Recombinant Human IL-19

In stock

Catalog ID

100-88

Size	Stock	SKU	Unit Price
10 µg	In Stock	100-88-10UG	$183.00
100 µg	In Stock	100-88-100UG	$705.00
500 µg	Inquire for Availability	100-88-500UG	$3,503.00
1 mg	In Stock	100-88-1MG	$5,839.00
10 µg (Animal-Free)	In Stock	100-88AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	100-88AF-100UG	$773.00
500 µg (Animal-Free)	In Stock	100-88AF-500UG	$3,857.00
1 mg (Animal-Free)	Inquire for Availability	100-88AF-1MG	$6,422.00

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Details

Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-a) expression in monocytes, and promotes T helper 2 (Th2) cell-mediated immune responses. IL-19 production is up-regulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	Melanoma differentiation associated-like protein
Accession Number	Q9UHD0
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 17.9 kDa (154 aa)
AA Sequence	MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MFSA
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	No biological activity data is available at this time	No biological activity data is available at this time

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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