Recombinant Human IGF-I

In stock

Catalog ID

100-34

Size	Stock	SKU	Unit Price
20 µg	Inquire for Availability	100-34-20UG	$73.00
100 µg	In Stock	100-34-100UG	$183.00
1 mg	In Stock	100-34-1MG	$305.00
5 mg	Inquire for Availability	100-34-5MG	$1,368.00
20 µg (Animal-Free)	Inquire for Availability	100-34AF-20UG	$79.00
100 µg (Animal-Free)	In Stock	100-34AF-100UG	$200.00
1 mg (Animal-Free)	In Stock	100-34AF-1MG	$335.00
5 mg (Animal-Free)	Inquire for Availability	100-34AF-5MG	$1,508.00

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Details

Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-I production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor I receptor (IGF-I receptor) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	Somatomedin C, mechano growth factor, IGF-IA
Accession Number	P05019
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 7.7 kDa (70 aa)
AA Sequence	GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	MCF-7 cell proliferation	0.3 - 1.5 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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