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Recombinant Human IFN-α 2b

In stock
Catalog ID
100-52
Size Stock SKU Unit Price Qty
20 µg In Stock 100-52-20UG
$73.00
    100 µg In Stock 100-52-100UG
    $183.00
      250 µg In Stock 100-52-250UG
      $378.00
        500 µg In Stock 100-52-500UG
        $632.00
          1 mg In Stock 100-52-1MG
          $1,094.00
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            Details

            Interferon-alpha 2b (IFN-α 2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α 2b. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α 2b variant differs from IFN-α 2a by one amino acid.

            Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

            Instructions

            Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

            Technical Specifications

            Alternate Names Type I Interferon, Alpha 2
            Accession Number P01563
            Source Genetically modified E.coli
            Predicted Molecular Mass Monomer, 19.4 kDa (166 aa)
            AA Sequence MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
            Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
            Product Reconstitution Sterile water at 0.1 mg/mL
            Country of Origin USA

             

            Specification* Method of Determination Acceptance Criteria
            Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
            Endotoxin Kinetic LAL ≤ 0.1 EU/µg
            Biological Activity (ED50) Viral CPE assay using EMC virus on A549 cells ≤ 0.005 ng/mL; ≥ 2.0 x 108 units/mg

             

            *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

            IFN-alpha IFN alpha

            Specifications

            Storage
            At or below -20°C
            Shelf Life
            12 months from date of receipt when stored at -20°C to-80°C as supplied.
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