Recombinant Human GM-CSF

In stock

Catalog ID

100-08

Size	Stock	SKU	Unit Price
5 µg	In Stock	100-08-5UG	$73.00
20 µg	In Stock	100-08-20UG	$183.00
100 µg	In Stock	100-08-100UG	$457.00
500 µg	In Stock	100-08-500UG	$2,045.00
1 mg	In Stock	100-08-1MG	$3,406.00
5 µg (Animal-Free)	In Stock	100-08AF-5UG	$79.00
20 µg (Animal-Free)	In Stock	100-08AF-20UG	$200.00
100 µg (Animal-Free)	In Stock	100-08AF-100UG	$504.00
500 µg (Animal-Free)	In Stock	100-08AF-500UG	$2,251.00
1 mg (Animal-Free)	In Stock	100-08AF-1MG	$3,747.00

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Details

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is hematopoietic growth factor produced by endothelial cells, monocytes, fibroblasts, and T cells. GM-CSF stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells. GM-CSF promotes immune system development and regulates neutrophil function during infection. Human and mouse GM-CSF show no cross-reactivity.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	CSF-2, Pluripoietin-α, MGI-1GM
Accession Number	P04141
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 14.6 kDa (128 aa)
AA Sequence	MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS-PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	TF-1 cell proliferation	≤ 0.2 ng/mL; ≥ 5.0 x 10⁶ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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