Recombinant Human GDNF

In stock

Catalog ID

100-02

Size	Stock	SKU	Unit Price
10 µg	In Stock	100-02-10UG	$183.00
100 µg	In Stock	100-02-100UG	$705.00
500 µg	In Stock	100-02-500UG	$3,503.00
1 mg	In Stock	100-02-1MG	$5,839.00
10 µg (Animal-Free)	In Stock	100-02AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	100-02AF-100UG	$773.00
500 µg (Animal-Free)	In Stock	100-02AF-500UG	$3,857.00
1 mg (Animal-Free)	In Stock	100-02AF-1MG	$6,422.00

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Details

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	ATF-1
Accession Number	P39905
Source	Genetically modified E.coli
Predicted Molecular Mass	Dimer, 15.2/30.4 kDa (135/270 aa)
AA Sequence	MSPDKQMAVL PRRERNRQAA AANPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCDAAETTY DKILKNLSRN RRLVSDKVGQ ACCRPIAFDD DLSFLDDNLV YHILRKHSAK RCGCI
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium citrate, 100 mM sodium chloride, pH 4.0
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	C6 proliferation	≤ 3 µg/mL; ≥ 3.3 x 10² units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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