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Recombinant Human GDF-5

In stock
Catalog ID
100-71
Size Stock SKU Unit Price Qty
10 µg In Stock 100-71-10UG
$73.00
    50 µg In Stock 100-71-50UG
    $183.00
      100 µg In Stock 100-71-100UG
      $330.00
        500 µg In Stock 100-71-500UG
        $839.00
          1 mg In Stock 100-71-1MG
          $1,460.00
            reset
            Details

            Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) and transforming growth factor beta (TGF-β) families and functions to regulate cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is expressed in the central nervous system and promotes the survival of dopaminergic neurons in animal models of Parkinson’s disease. GDF-5 is also important during chondrogenesis and chondrocyte differentiation.

            Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

            Instructions

            Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

            Technical Specifications

            Alternate Names CDMP-1
            Accession Number P43026
            Source Genetically modified E.coli
            Predicted Molecular Mass Dimer, 13.7/27.4 kDa (121/242 aa)
            AA Sequence MAPLATRQGK RPSKNLKARC SRKALHVNFK DMGWDDWIIA PLEYEAFHCE GLCEFPLRSH LEPTNHAVIQ TLMNSMDPES TPPTCCVPTR LSPISILFIDSA NNVVYKQY EDMVVESCGC R
            Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
            Product Reconstitution Sterile water at 0.1 mg/mL
            Country of Origin USA

             

            Specification* Method of Determination Acceptance Criteria
            Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
            Endotoxin Kinetic LAL ≤ 0.1 EU/µg
            Biological Activity (ED50) Alkaline phosphatase activity in ATDC5 cells ≤ 1200 ng/mL

             

            *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

            Specifications

            Storage
            At or below -20°C
            Shelf Life
            12 months from date of receipt when stored at -20°C to-80°C as supplied.
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