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Recombinant Human FLT-3 Ligand

In stock
Catalog ID
100-21
Size Stock SKU Unit Price Qty
10 µg In Stock 100-21-10UG
$183.00
    100 µg In Stock 100-21-100UG
    $529.00
      500 µg In Stock 100-21-500UG
      $2,627.00
        1 mg In Stock 100-21-1MG
        $4,379.00
          10 µg (Animal-Free) In Stock 100-21AF-10UG
          $200.00
            100 µg (Animal-Free) In Stock 100-21AF-100UG
            $577.00
              500 µg (Animal-Free) In Stock 100-21AF-500UG
              $2,889.00
                1 mg (Animal-Free) In Stock 100-21AF-1MG
                $4,817.00
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                  Details

                  Fms-related tyrosine kinase 3 ligand (FLT-3 ligand) is a growth factor that regulates hematopoietic cell proliferation. FLT-3 ligand signalling is transmitted through the fms-related tyrosine kinase 3 (FLT-3) receptor. FLT-3 ligand promotes the long-term expansion and differentiation of pro-B cells in the presence of interleukin 7 (IL-7) or in combination of IL-7 and interleukin 3 (IL-3). Human FLT-3 ligand is active on mouse cells.

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                  Instructions

                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names Flt3L, Fms-related tyrosine kinase 3 ligand
                  Accession Number P49771
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Monomer, 17.7 kDa (155 aa)
                  AA Sequence MTQDCSFQHS PISSDFAVKI RELSDYLLQD YPVTVASNLQ DEELCGGLWR LVLAQRWMER LKTVAGSKMQ GLLERVNTEI HFVTKCAFQP PPSCLRFVQT NISRLLQETS EQLVALKPWI TRQNFSRCLE LQCQPDSSTL PPPWSPRPLE ATAPT
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, 50 mM NaCl, pH 7.5
                  Product Reconstitution Sterile water at 0.1 mg/mL
                  Country of Origin USA

                   

                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 97%
                  Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                  Biological Activity (ED50) OCI-AML5 cell proliferation ≤ 5 ng/mL; ≥ 2.0 x 105 units/mg

                   

                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                  Specifications

                  Storage
                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to-80°C as supplied.
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