Recombinant Human FGF-acidic / FGF-1

In stock

Catalog ID

100-29

Size	Stock	SKU	Unit Price
10 µg	In Stock	100-29-10UG	$73.00
50 µg	In Stock	100-29-50UG	$183.00
100 µg	In Stock	100-29-100UG	$330.00
500 µg	Inquire for Availability	100-29-500UG	$839.00
1 mg	Inquire for Availability	100-29-1MG	$1,460.00
10 µg (Animal-Free)	In Stock	100-29AF-10UG	$79.00
50 µg (Animal-Free)	In Stock	100-29AF-50UG	$200.00
100 µg (Animal-Free)	In Stock	100-29AF-100UG	$359.00
500 µg (Animal-Free)	Inquire for Availability	100-29AF-500UG	$925.00
1 mg (Animal-Free)	Inquire for Availability	100-29AF-1MG	$1,607.00

Find Your Distributor

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Details

Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	FGF1, HBGF-1, Beta-endothelial growth factor, ECGF-beta
Accession Number	P05230
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 16 kDa (141 aa)
AA Sequence	MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, 150 mM sodium sulfate, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	NR6R-3T3 cell proliferation	≤ 2 ng/mL; ≥ 5.0 x 10⁵ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

COA Search

Certificates of Analysis Search