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Recombinant Human FGF-acidic / FGF-1

In stock
Catalog ID
100-29
Size Stock SKU Unit Price Qty
10 µg In Stock 100-29-10UG
$73.00
    50 µg In Stock 100-29-50UG
    $183.00
      100 µg In Stock 100-29-100UG
      $330.00
        500 µg Inquire for Availability 100-29-500UG
        $839.00
          1 mg Inquire for Availability 100-29-1MG
          $1,460.00
            10 µg (Animal-Free) In Stock 100-29AF-10UG
            $79.00
              50 µg (Animal-Free) In Stock 100-29AF-50UG
              $200.00
                100 µg (Animal-Free) Inquire for Availability 100-29AF-100UG
                $359.00
                  500 µg (Animal-Free) Inquire for Availability 100-29AF-500UG
                  $925.00
                    1 mg (Animal-Free) Inquire for Availability 100-29AF-1MG
                    $1,607.00
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                      Details

                      Acidic fibroblast growth factor (FGF-acidic), also known as FGF-1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-acidic regulates cardiogenesis through protein kinase C signaling. FGF-acidic also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of FGF-acidic are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of FGF-acidic during T2DM.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.  

                      Technical Specifications

                      Alternate Names FGF1, HBGF-1, Beta-endothelial growth factor, ECGF-beta
                      Accession Number P05230
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Monomer, 16 kDa (141 aa)
                      AA Sequence MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, 150 mM sodium sulfate, pH 7.5
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) NR6R-3T3 cell proliferation ≤ 2 ng/mL; ≥ 5.0 x 105 units/mg

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to -80°C as supplied.
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