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Recombinant Human FGF-7 / KGF

In stock
Catalog ID
100-187
Size Stock SKU Unit Price Qty
10 µg In Stock 100-187-10UG
$183.00
    100 µg In Stock 100-187-100UG
    $705.00
      500 µg Inquire for Availability 100-187-500UG
      $3,503.00
        1 mg In Stock 100-187-1MG
        $5,839.00
          10 µg (Animal-Free) Inquire for Availability 100-187AF-10UG
          $200.00
            100 µg (Animal-Free) In Stock 100-187AF-100UG
            $773.00
              500 µg (Animal-Free) In Stock 100-187AF-500UG
              $3,857.00
                1 mg (Animal-Free) In Stock 100-187AF-1MG
                $6,422.00
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                  Details

                  Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFR2-IIIb). The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells. FGF-7 also induces the formation of the apical ectodermal ridge during limb development.

                  Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                  Instructions

                  Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                  Technical Specifications

                  Alternate Names KGF
                  Accession Number P21781
                  Source Genetically modified E.coli
                  Predicted Molecular Mass Monomer, 19 kDa (164 aa)
                  AA Sequence MACNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK KEQKTAHFLP MAIT
                  Formulation Lyophilized from a 0.2 µm filtered solution containing 20 mM sodium phosphate, 0.5 M sodium chloride, pH 7.5
                  Product Reconstitution Sterile water at 0.1 mg/mL (reconstitution at concentrations > 0.1 mg/mL may result in a precipitate)
                  Country of Origin USA

                   

                  Specification* Method of Determination Acceptance Criteria
                  Purity Reducing and Non-Reducing SDS PAGE ≥ 90%
                  Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                  Biological Activity (ED50) 4MBr-5 cell proliferation ≤ 60 ng/mL; ≥ 1.7 x 104 units/mg

                   

                  *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                  Specifications

                  Storage
                  At or below -20°C
                  Shelf Life
                  12 months from date of receipt when stored at -20°C to -80°C as supplied.
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