Recombinant Human EBI3 subunit (IL-27 / IL-35)

In stock

Catalog ID

100-162

Size	Stock	SKU	Unit Price
5 µg	In Stock	100-162-5UG	$73.00
20 µg	In Stock	100-162-20UG	$183.00
100 µg	In Stock	100-162-100UG	$705.00
500 µg	Inquire for Availability	100-162-500UG	$3,503.00
1 mg	Inquire for Availability	100-162-1MG	$5,839.00
5 µg (Animal-Free)	In Stock	100-162AF-5UG	$79.00
20 µg (Animal-Free)	In Stock	100-162AF-20UG	$200.00
100 µg (Animal-Free)	In Stock	100-162AF-100UG	$773.00
500 µg (Animal-Free)	Inquire for Availability	100-162AF-500UG	$3,857.00
1 mg (Animal-Free)	Inquire for Availability	100-162AF-1MG	$6,422.00

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Details

Epstein-Barr virus induced gene-3 (EBI3) is a secreted glycoprotein belonging to the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). EBI3 expression is induced in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form interleukin 27 (IL-27), and with p35 to form interleukin 35 (IL-35). Both IL-27 and IL-35 have anti-inflammatory and regulatory activity.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	IL-35/EBI3, IL-27/EBI3
Accession Number	Q14213
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 23.4 kDa (210 aa)
AA Sequence	MRKGPPAALT LPRVQCRASR YPIAVDCSWT LPPAPNSTSP VSFIATYRLG MAARGHSWPC LQQTPTSTSC TITDVQLFSM APYVLNVTAV HPWGSSSSFV PFITEHIIKP DPPEGVRLSP LAERQLQVQW EPPGSWPFPE IFSLKYWIRY KRQGAARFHR VGPIEATSFI LRAVRPRARY YVQVAAQDLT DYGELSDWSL PATATMSLGK
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) + 0.5% mannitol
Product Reconstitution	Sterile 10 mM HCl at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 90%
Endotoxin	Kinetic LAL	≤ 5 EU/µg
Biological Activity (ED₅₀)	No biological activity data is available at this time	No biological activity data is available at this time

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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