Recombinant Human BDNF

In stock

Catalog ID

100-01

Size	Stock	SKU	Unit Price
10 µg	In Stock	100-01-10UG	$183.00
100 µg	In Stock	100-01-100UG	$705.00
500 µg	In Stock	100-01-500UG	$3,503.00
1 mg	In Stock	100-01-1MG	$5,839.00
10 µg (Animal-Free)	In Stock	100-01AF-10UG	$200.00
100 µg (Animal-Free)	In Stock	100-01AF-100UG	$779.00
500 µg (Animal-Free)	In Stock	100-01AF-500UG	$3,857.00
1 mg (Animal-Free)	In Stock	100-01AF-1MG	$6,422.00

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Details

Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival. BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	None
Accession Number	P23560
Source	Genetically modified E.coli
Predicted Molecular Mass	Noncovalent Homodimer, 13.6/27.3 kDa (120/240 aa)
AA Sequence	MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	Proliferation of a neuroblastoma cell line stably expressing TrkB (BR6)	≤ 40 ng/mL; 2.5 x 10⁴ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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