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Go from “Good Enough” to Optimal Cell Culture Media

Not all cell lines are created equal—and neither is their associated media. To achieve the desired target performance, the design and development of an optimal cell culture medium demands additional improvement intended specifically…

Quality Media by Design

Current Good Manufacturing Practices (cGMP) guidelines are regulations provided by the United States Food and Drug Administration (FDA) to ensure the safety and efficacy of products manufactured by food, pharmaceutical and medical device companies.…

Cell, Media, and Process – The Three Musketeers of Cell Culture

Optimal cell culture performance requires the cells, the media, and the process all work together closely in harmony. Much like the legendary Three Musketeers from Alexandre Dumas’ 19th century novel, these three fundamental aspects…

Vitrification - A front-runner of human oocyte and embryo cryopreservation technology

Cryopreservation involves the cooling of living cells and tissues down to minus 196°C to arrest all biological activities and preserve them for future use. In assisted reproductive technology (ART), the preservation of both sperm…

The impact of serum and serum-derived undefined biologic modifiers in cell culture

Since its first description in 1885 by Wilhelm Roux, cell culture has become the quintessential tool in basic and translational biological research and with cells becoming an advanced medical product in the field of…

Media Design for the Fed-Batch Production of Antibodies

Effective production of therapeutic antibodies requires optimal cell growth for peak yields. Efficiently maximizing antibody production typically requires a cell growth curve with a rapid rise to maximal viable cell density that plateaus for…