Your partner for all cytogenetic applications

Each specialized medium in the CHANG portfolio is optimized to produce superior growth and morphology in cytogenetic samples. They are complemented by a range of classical media, salts, buffers, and reagents. Our media are cGMP manufactured and performance tested for peace of mind.

Rely on CHANG media for successful analysis

For over 30 years, FUJIFILM Irvine Scientific has been a world leader in providing a comprehensive range of products tailored for cytogenetic laboratories. CHANG, the original medium designed specifically for cytogenetic applications has been the gold-standard for decades. Our current CHANG portfolio builds on that foundation with modern formulas. Each cell- or tissue-specific medium is optimized to produce superior growth and morphology in peripheral blood, bone marrow, amniotic fluid, chorionic villi (CVS) and product of conception (POC) samples.

Quality, performance, and support

With an unrivalled Quality System focused on risk mitigation and quality assurance, you can rely on CHANG media for quality, consistency, and exceptional performance. Our media meet regulatory standards for FDA 510k and CE Mark and are manufactured in compliance with cGMP guidelines.

We are renowned for our individualized customer service to support your lab with services such as lot hold policies and expert technical support from experienced cytogeneticists.

Each cytogenetic sample is precious—making the media used an indispensable tool for successful analysis. This is the reason many leading laboratories rely on CHANG media for all their cytogenetic applications.

At a Glance

Success with CHANG Marrow

Featured Case Study

CHANG Marrow® is the product of choice for ResearchDX, a Contract Diagnostics Organization that takes personalized medicine to the next level.

CHANG Marrow

Featured Product

CHANG Marrow is a complete, ready-to-use medium optimized to support bone marrow cultures for karyotyping and other genetic testing of various hematological disorders. After an extensive optimization process to create a superior, innovative blend of growth factors, Irvine Scientific’s…


Featured Product

CHANG Amnio is a complete, ready-to-use medium with an antibiotic developed for the culture of human amniotic fluid cells, chorionic villi sampling, and tissues for use in karyotyping and other antenatal testing. With an improved blend of basal media…