Y-27632 (GMP-compliant)

It is a selective and potent inhibitor of ROCK (Rho-associated coiled-coil forming kinase/Rho binding kinase). Y-27632 has a variety of activities including vascular smooth muscle contraction through the ROCK signaling (Ki = 140 nmol/L p160ROCK). This product has been reported to suppress death of human ES/iPS cells at the time of cell dispersion and improves viability of the cells after cryopreservation.

This product complies with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.

For Cell Culture

Manufacturer:	FUJIFILM Wako Pure Chemical Corporation
Specification Assay:	99.5+% (HPLC)
CAS RN:	331752-47-7
Molecular Formula:	C14H21N3O・2HCl・H2O
Molecular Weight:	338.27
GHS:	Warning
Appearance:	White - pale yellowish white, crystalline powder or powder
Specific Rotation:	+2.0 - +10.0 degrees (D/20°C)
Purity:	Bacterial endotoxins : <0.25EU/mg
Alias:	((R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)cyclohexanecarboxamide Dihydrochloride Monohydrate)

* Click to move to the PubMed Central search results.
** This product is complied with ICH-Q7 (GMP for APIs) as a raw material for commercial production of regenerative medicine products.
*** The manufacturing process and analytical procedure are validated.

Made by FUJIFILM Wako Pure Chemical Corporation and distributed by FUJIFILM Irvine Scientific 

• For research use or further manufacturing use only. Not for use in diagnostic procedures. 
• Product content may differ from the actual image due to minor specification changes etc. 
• If the revision of product standards and packaging standards has been made, there is a case where the actual product specifications and images are different.