Q. How do we prevent mycoplasma contamination in cell culture?
A. Good aseptic techniques should be used in all laboratory applications. The best method for prevention is to test all materials that come in contact with the cells. This should be done on a regular basis to ensure that mycoplasma is not introduced into the cell culture and to identify any potential sources of contamination.
Q. Should I be concerned with mycoplasma in my cell culture?
A. Mycoplasma contamination should always be a concern. Mycoplasma contamination can change the morphology of the cells and interfere with bioassays, cell growth, viability, and production.