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Recombinant Rat IL-10

In stock
Catalog ID
300-35
Size Stock SKU Unit Price Qty
5 µg In Stock 300-35-5UG
$73.00
    20 µg In Stock 300-35-20UG
    $183.00
      100 µg In Stock 300-35-100UG
      $705.00
        500 µg Inquire for Availability 300-35-500UG
        $2,627.00
          1 mg Inquire for Availability 300-35-1MG
          $5,839.00
            5 µg (Animal-Free) Inquire for Availability 300-35AF-5UG
            $79.00
              20 µg (Animal-Free) Inquire for Availability 300-35AF-20UG
              $200.00
                100 µg (Animal-Free) Inquire for Availability 300-35AF-100UG
                $779.00
                  500 µg (Animal-Free) Inquire for Availability 300-35AF-500UG
                  $2,889.00
                    1 mg (Animal-Free) Inquire for Availability 300-35AF-1MG
                    $6,422.00
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                      Details

                      Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-γ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells. IL-10 also suppresses antigen presentation on antigen presenting cells, and enhances the survival, proliferation, and antibody production of B cells.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                      Technical Specifications

                      Alternate Names Cytokine synthesis inhibitory factor, CSIF
                      Accession Number P29456
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Monomer, 18.8 kDa (161 aa)
                      AA Sequence MSKGHSIRGD NNCTHFPVSQ THMLRELRAA FSQVKTFFQK KDQLDNILLT DSLLQDFKGY LGCQALSEMI KFYLVEVMPQ AENHGPEIKE HLNSLGEKLK TLWIQLRRCH RFLPCENKSK AVEQVKNDFN KLQDKGVYKA MNEFDIFINC IEAYVTLKMK N
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to-80°C as supplied.
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