Recombinant Mouse IL-33

In stock

Catalog ID

200-36

Size	Stock	SKU	Unit Price
10 µg	In Stock	200-36-10UG	$183.00
100 µg	In Stock	200-36-100UG	$705.00
500 µg	In Stock	200-36-500UG	$3,503.00
1 mg	Inquire for Availability	200-36-1MG	$5,839.00
10 µg (Animal-Free)	Inquire for Availability	200-36AF-10UG	$200.00
100 µg (Animal-Free)	Inquire for Availability	200-36AF-100UG	$773.00
500 µg (Animal-Free)	Inquire for Availability	200-36AF-500UG	$3,857.00
1 mg (Animal-Free)	Inquire for Availability	200-36AF-1MG	$6,422.00

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Details

Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	NP-HEV
Accession Number	Q8BVZ5
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 17.7 kDa (159 aa)
AA Sequence	MSIQGTSLLT QSPASLSTYN DQSVSFVLEN GCYVINVDDS GKDQEQDQVL LRYYESPCPA SQSGDGVDGK KLMVNMSPIK DTDIWLHAND KDYSVELQRG DVSPPEQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEEKDESCN NIMFKLSKI
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 90%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	D10S cell proliferation	≤ 2 ng/mL; ≥ 5.0 x 10⁵ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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