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Recombinant Mouse IL-17E / (IL-25)
Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17RB receptor to stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine and to induce the activation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB).
Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.
Instructions
Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.
Technical Specifications
Alternate Names | IL-25 |
Accession Number | Q8VHC9 |
Source | Genetically modified E.coli |
Predicted Molecular Mass | Dimer, 17.6/35.2 kDa (154/308 aa) |
AA Sequence | MVSLRIQEGC SHLPSCCPSK EQEPPEEWLK WSSASVSPPE PLSHTHHAES CRASKDGPLN SRAISPWSYE LDRDLNRVPQ DLYHARCLCP HCVSLQTGSH MDPLGNSVPL YHNQTVFYRR PCHGEEGTHR RYCLERRLYR VSLACVCVRP RVMA |
Formulation | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
Product Reconstitution | Sterile 10 mM HCl at 0.1 mg/mL |
Country of Origin | USA |
Specification* | Method of Determination | Acceptance Criteria |
Purity | Reducing and Non-Reducing SDS PAGE | ≥ 95% |
Endotoxin | Kinetic LAL | ≤ 0.1 EU/µg |
Biological Activity (ED50) | No biological activity data is available at this time | No biological activity data is available at this time |
*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.