Recombinant Mouse IL-11

In stock

Catalog ID

200-64

Size	Stock	SKU	Unit Price
10 µg	In Stock	200-64-10UG	$183.00
100 µg	In Stock	200-64-100UG	$705.00
500 µg	Inquire for Availability	200-64-500UG	$3,503.00
1 mg	Inquire for Availability	200-64-1MG	$5,839.00
10 µg (Animal-Free)	Inquire for Availability	200-64AF-10UG	$200.00
100 µg (Animal-Free)	Inquire for Availability	200-64AF-100UG	$773.00
500 µg (Animal-Free)	Inquire for Availability	200-64AF-500UG	$3,857.00
1 mg (Animal-Free)	Inquire for Availability	200-64AF-1MG	$6,422.00

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Details

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	AGIF (Adipogenesis Inhibitory Factor), oprelvekin
Accession Number	P47873
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 19.3 kDa (179 aa)
AA Sequence	MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	B9 cell proliferation	≤ 250 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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