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Recombinant Human IL-7

In stock
Catalog ID
100-11
Size Stock SKU Unit Price Qty
10 µg Inquire for Availability 100-11-10UG
$183.00
10 µg (Animal-Free) Inquire for Availability 100-11AF-10UG
$200.00
100 µg Inquire for Availability 100-11-100UG
$705.00
100 µg (Animal-Free) Inquire for Availability 100-11AF-100UG
$773.00
500 µg Inquire for Availability 100-11-500UG
$3,503.00
500 µg (Animal-Free) Inquire for Availability 100-11AF-500UG
$3,857.00
1 mg Inquire for Availability 100-11-1MG
$5,839.00
1 mg (Animal-Free) Inquire for Availability 100-11AF-1MG
$6,422.00
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Details

Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names Lymphopoietin 1 (LP-1), pre-B cell Factor
Accession Number P13232
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 17.5 kDa (153 aa)
AA Sequence MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Formulation Lyophilized from a 0.2 µm filtered solution containing 20 mM Sodium Phosphate, pH 7.5
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 97%
Endotoxin Kinetic LAL ≤ 1 EU/µg
Biological Activity (ED50) PHA stimulated human PBMC ≤ 0.5 ng/mL; ≥ 2.0 x 106 units/mg

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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