Recombinant Human IL-6

In stock

Catalog ID

100-10

Size	Stock	SKU	Unit Price
5 µg	In Stock	100-10-5UG	$73.00
20 µg	In Stock	100-10-20UG	$183.00
100 µg	In Stock	100-10-100UG	$457.00
500 µg	In Stock	100-10-500UG	$1,971.00
1 mg	In Stock	100-10-1MG	$3,284.00
5 µg (Animal-Free)	In Stock	100-10AF-5UG	$79.00
20 µg (Animal-Free)	In Stock	100-10AF-20UG	$200.00
100 µg (Animal-Free)	In Stock	100-10AF-100UG	$504.00
500 µg (Animal-Free)	In Stock	100-10AF-500UG	$2,165.00
1 mg (Animal-Free)	In Stock	100-10AF-1MG	$3,613.00

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Details

Interleukin 6 (IL-6) is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages and muscle cells. IL-6 signals through a receptor complex containing two receptors, IL-6Rα and gp130. IL-6 has an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines. Human IL-6 is active on mouse and rat cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	IFN-β2, B-cell Differentiation Factor, BSF-2, HSF, MGI-2
Accession Number	P05231
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 21 kDa (185 aa)
AA Sequence	MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 97%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	B9 cell proliferation	≤ 0.025 ng/mL; ≥ 4.0 x 10⁷ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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