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Recombinant Human IL-6

In stock
Catalog ID
100-10
Size Stock SKU Unit Price Qty
5 µg In Stock 100-10-5UG
$73.00
5 µg (Animal-Free) In Stock 100-10AF-5UG
$79.00
20 µg In Stock 100-10-20UG
$183.00
20 µg (Animal-Free) In Stock 100-10AF-20UG
$200.00
100 µg In Stock 100-10-100UG
$457.00
100 µg (Animal-Free) In Stock 100-10AF-100UG
$504.00
500 µg In Stock 100-10-500UG
$1,971.00
500 µg (Animal-Free) In Stock 100-10AF-500UG
$2,165.00
1 mg In Stock 100-10-1MG
$3,284.00
1 mg (Animal-Free) In Stock 100-10AF-1MG
$3,613.00
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Details

Interleukin 6 (IL-6) is an important pro-inflammatory and anti-inflammatory cytokine expressed by T cells, macrophages and muscle cells. IL-6 signals through a receptor complex containing two receptors, IL-6Rα and gp130. IL-6 has an important function in promoting fever and can serve to stimulate an immune response to trauma. IL-6 is often used for growth of hybridoma cell lines. Human IL-6 is active on mouse and rat cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names IFN-β2, B-cell Differentiation Factor, BSF-2, HSF, MGI-2
Accession Number P05231
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 21 kDa (185 aa)
AA Sequence MPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 97%
Endotoxin Kinetic LAL ≤ 1 EU/µg
Biological Activity (ED50) B9 cell proliferation ≤ 0.025 ng/mL; ≥ 4.0 x 107 units/mg

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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