Recombinant Human IL-2(C126S)

In stock

Catalog ID

100-222

Size	Stock	SKU	Unit Price
10 µg (Animal-Free)	In Stock	100-222AF-10UG	$99.00
50 µg (Animal-Free)	In Stock	100-222AF-50UG	$204.00
100 µg (Animal-Free)	In Stock	100-222AF-100UG	$230.00
1 mg (Animal-Free)	In Stock	100-222AF-1MG	$804.00

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Details

Interleukin 2_C126S (IL-2_C126S) is a cytokine primarily known for activating T cell proliferation. It also stimulates proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages. IL-2 is critical for the development, survival, and function of CD4⁺CD25⁺ regulatory T cells, which promote T cell tolerance by suppressing their responses to self-antigens, inhibiting immune responses and preventing autoimmune diseases.

Product images on the website are not representative of actual products, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	T cell growth factor, TCGF, Aldesleukin
Accession Number	P60568
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 15.5kDa (134 aa)
AA Sequence	MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFSQSII STLT
Formulation	Recombinant human IL-2_C126S is lyophilized from a 0.2 μm filtered solution containing 0.1% trifluoroacetic acid
Product Reconstitution	Sterile 10 mM HCl at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Coomassie staining	≥ 97%
Endotoxin	Kinetic LAL	≤ 0.01 EU/µg
Biological Activity (ED₅₀)	CTLL-2 cell proliferation	≤ 3 ng/mL; ≥ 3.3 x 10⁶ units/mg

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied

FAQs

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