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Recombinant Human IL-19

In stock
Catalog ID
100-88
Size Stock SKU Unit Price Qty
10 µg In Stock 100-88-10UG
$183.00
10 µg (Animal-Free) In Stock 100-88AF-10UG
$200.00
100 µg In Stock 100-88-100UG
$705.00
100 µg (Animal-Free) In Stock 100-88AF-100UG
$773.00
500 µg Inquire for Availability 100-88-500UG
$3,503.00
500 µg (Animal-Free) In Stock 100-88AF-500UG
$3,857.00
1 mg Inquire for Availability 100-88-1MG
$5,839.00
1 mg (Animal-Free) In Stock 100-88AF-1MG
$6,422.00
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Details

Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-a) expression in monocytes, and promotes T helper 2 (Th2) cell-mediated immune responses. IL-19 production is up-regulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names Melanoma differentiation associated-like protein
Accession Number Q9UHD0
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 17.9 kDa (154 aa)
AA Sequence MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MFSA
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 1 EU/µg
Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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