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Recombinant Human IL-11

In stock
Catalog ID
100-84
Size Stock SKU Unit Price Qty
10 µg Inquire for Availability 100-84-10UG
$183.00
10 µg (Animal-Free) In Stock 100-84AF-10UG
$200.00
100 µg In Stock 100-84-100UG
$705.00
100 µg (Animal-Free) In Stock 100-84AF-100UG
$779.00
500 µg In Stock 100-84-500UG
$3,503.00
500 µg (Animal-Free) Inquire for Availability 100-84AF-500UG
$3,857.00
1 mg Inquire for Availability 100-84-1MG
$5,839.00
1 mg (Animal-Free) Inquire for Availability 100-84AF-1MG
$6,422.00
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Details

Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Rα receptor to activate JAK downstream signaling. Human IL-11 shows activity on murine cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names AGIF (Adipogenesis Inhibitory Factor), oprelvekin
Accession Number P20809
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 19.3 kDa (179 aa)
AA Sequence MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) TF-1 cell proliferation ≤ 10 ng/mL; ≥ 1.0 x 105 units/mg

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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