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Recombinant Human IGF-II

In stock
Catalog ID
100-14
Size Stock SKU Unit Price Qty
10 µg In Stock 100-14-10UG
$73.00
10 µg (Animal-Free) In Stock 100-14AF-10UG
$79.00
50 µg In Stock 100-14-50UG
$183.00
50 µg (Animal-Free) In Stock 100-14AF-50UG
$200.00
100 µg Inquire for Availability 100-14-100UG
$330.00
100 µg (Animal-Free) In Stock 100-14AF-100UG
$359.00
500 µg Inquire for Availability 100-14-500UG
$766.00
500 µg (Animal-Free) Inquire for Availability 100-14AF-500UG
$847.00
1 mg Inquire for Availability 100-14-1MG
$1,338.00
1 mg (Animal-Free) Inquire for Availability 100-14AF-1MG
$1,472.00
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Details

Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names Somatomedin A
Accession Number P01344
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 7.5 kDa (67 aa)
AA Sequence AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) Human breast cancer cell line MCF-7 ≤ 6 ng/mL; ≥ 1.7 x 105 units/mg

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to -80°C as supplied.
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