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Recombinant Human RANK Ligand

In stock
Catalog ID
100-19
Size Stock SKU Unit Price Qty
10 µg Inquire for Availability 100-19-10UG
$176.00
10 µg (Animal-Free) In Stock 100-19AF-10UG
$192.00
100 µg In Stock 100-19-100UG
$678.00
100 µg (Animal-Free) In Stock 100-19AF-100UG
$743.00
500 µg Inquire for Availability 100-19-500UG
$3,368.00
500 µg (Animal-Free) Inquire for Availability 100-19AF-500UG
$3,709.00
1 mg Inquire for Availability 100-19-1MG
$5,614.00
1 mg (Animal-Free) Inquire for Availability 100-19AF-1MG
$6,175.00
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Details

Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names TNFSF11, TRANCE, OPGL, ODF
Accession Number O14788
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 19.7 kDa (175 aa)
AA Sequence EKAMVDGSWL DLAKRSKLEA QPFAHLTINA TDIPSGSHKV SLSSWYHDRG WAKISNMTFS NGKLIVNQDG FYYLYANICF RHHETSGDLA TEYLQLMVYV TKTSIKIPSS HTLMKGGSTK YWSGNSEFHF YSINVGGFFK LRSGEEISIE VSNPSLLDPD QDATYFGAFK VRDID
Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 1 EU/µg
Biological Activity (ED50) Activity of RAW-Blue cells ≤ 50 ng/mL

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to -80°C as supplied.
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