Recombinant Human RANK Ligand

In stock

Catalog ID

100-19

Size	Stock	SKU	Unit Price
10 µg	Inquire for Availability	100-19-10UG	$176.00
10 µg (Animal-Free)	In Stock	100-19AF-10UG	$192.00
100 µg	In Stock	100-19-100UG	$678.00
100 µg (Animal-Free)	In Stock	100-19AF-100UG	$743.00
500 µg	Inquire for Availability	100-19-500UG	$3,368.00
500 µg (Animal-Free)	Inquire for Availability	100-19AF-500UG	$3,709.00
1 mg	Inquire for Availability	100-19-1MG	$5,614.00
1 mg (Animal-Free)	Inquire for Availability	100-19AF-1MG	$6,175.00

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Details

Receptor activator of nuclear factor kappa-B Ligand (RANK Ligand) is a cell-bound marker related to the tumor necrosis factor (TNF) family of proteins. RANK Ligand plays a critical role in bone metabolism and osteoclast differentiation. T cell expression of RANK Ligand promotes dendritic cell maturation.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	TNFSF11, TRANCE, OPGL, ODF
Accession Number	O14788
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 19.7 kDa (175 aa)
AA Sequence	EKAMVDGSWL DLAKRSKLEA QPFAHLTINA TDIPSGSHKV SLSSWYHDRG WAKISNMTFS NGKLIVNQDG FYYLYANICF RHHETSGDLA TEYLQLMVYV TKTSIKIPSS HTLMKGGSTK YWSGNSEFHF YSINVGGFFK LRSGEEISIE VSNPSLLDPD QDATYFGAFK VRDID
Formulation	Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 1 EU/µg
Biological Activity (ED₅₀)	Activity of RAW-Blue cells	≤ 50 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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