Recombinant Human / Mouse IHH

In stock

Catalog ID

800-05

Size	Stock	SKU	Unit Price
5 µg	In Stock	800-05-5UG	$73.00
25 µg	In Stock	800-05-25UG	$183.00
100 µg	In Stock	800-05-100UG	$457.00
500 µg	Inquire for Availability	800-05-500UG	$1,825.00
1 mg	Inquire for Availability	800-05-1MG	$3,041.00
5 µg (Animal-Free)	Inquire for Availability	800-05AF-5UG	$79.00
25 µg (Animal-Free)	In Stock	800-05AF-25UG	$200.00
100 µg (Animal-Free)	In Stock	800-05AF-100UG	$504.00
500 µg (Animal-Free)	Inquire for Availability	800-05AF-500UG	$2,008.00
1 mg (Animal-Free)	Inquire for Availability	800-05AF-1MG	$3,346.00

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Details

Indian hedgehog (IHH) is an essential signaling factor that is secreted in the gut, cartilage, and bone during embryonic development. IHH acts through the patched (PTC) receptor to induce transcriptional changes important for bone and cartilage development. IHH also induces the expression of parathyroid hormone-related peptide (PTHrP), which in turn mediates IHH activity during chondrocyte differentiation, forming a negative feedback loop.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	HHG-2
Accession Number	Q14623/P97812
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 19.9 kDa (177 aa)
AA Sequence	MIIGPGRVVG‚ SRRRPPRKLV‚ PLAYKQFSPN‚ VPEKTLGASG‚ RYEGKIARSS‚ ERFKELTPNY‚ NPDIIFKDEE‚ NTGADRLMTQRCKDRLNSLA‚ ISVMNQWPGV‚ KLRVTEGWDE‚ DGHHSEESLH‚ YEGRAVDITT‚ SDRDRNKYGL‚ LARLAVEAGF‚ DWVYYESKAH‚ VHCSVKSEHSAAAKTGG
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	10 mM HCl at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	No biological activity data is available at this time	No biological activity data is available at this time

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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