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Recombinant Human BAFF / BLyS

In stock
Catalog ID
100-24
Size Stock SKU Unit Price Qty
5 µg In Stock 100-24-5UG
$73.00
5 µg (Animal-Free) Inquire for Availability 100-24AF-5UG
$79.00
20 µg In Stock 100-24-20UG
$183.00
20 µg (Animal-Free) Inquire for Availability 100-24AF-20UG
$200.00
100 µg In Stock 100-24-100UG
$705.00
100 µg (Animal-Free) Inquire for Availability 100-24AF-100UG
$773.00
500 µg Inquire for Availability 100-24-500UG
$3,503.00
500 µg (Animal-Free) Inquire for Availability 100-24AF-500UG
$3,857.00
1 mg Inquire for Availability 100-24-1MG
$5,839.00
1 mg (Animal-Free) Inquire for Availability 100-24AF-1MG
$6,422.00
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Details

B cell-activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a type II member of the tumor necrosis factor (TNF) superfamily. BAFF is expressed as a transmembrane protein on T cells, macrophages, and dendritic cells. The transmembrane domain of BAFF can also be cleaved to produce a soluble protein fragment. BAFF binds to the TNF receptors known as B cell maturation antigen (BCMA), transmembrane activator and CAML interactor (TACI), and BAFF receptor (BAFFR). BAFF is important for the survival and maturation of peripheral B cells. Human BAFF shows activity on mouse splenocytes.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names TALL, BLyS, THANK
Accession Number Q9Y275
Source Genetically modified E.coli
Predicted Molecular Mass Monomer, 18.5 kDa (163 aa)
AA Sequence MHHHHHHLVP RAVQGPEETV TQDCLQLIAD SETPTIQKGS YTFVPWLLSF KRGSALEEKE NKILVKETGY FFIYGQVLYT DKTYAMGHLI QRKKVHVFGD ELSLVTLFRC IQNMPETLPN NSCYSAGIAK LEEGDELQLA IPRENAQISL DGDVTFFGAL KLL
Formulation Lyophilized from a 0.2 µm filtered solution containing 10 mM sodium phosphate, pH 7.5
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 90%
Endotoxin Kinetic LAL ≤ 1 EU/µg
Biological Activity (ED50) No biological activity data is available at this time No biological activity data is available at this time

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to-80°C as supplied.
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