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Recombinant Mouse VEGF-165

In stock
Catalog ID
200-34
Size Stock SKU Unit Price Qty
10 µg In Stock 200-34-10UG
$183.00
    100 µg In Stock 200-34-100UG
    $529.00
      500 µg In Stock 200-34-500UG
      $2,627.00
        1 mg Inquire for Availability 200-34-1MG
        $4,379.00
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          Details

          Vascular endothelial growth factor A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

          Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

          Instructions

          Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

          Technical Specifications

          Alternate Names VEGF-A, VPF, glioma-derived endothelial cell mitogen
          Accession Number Q00731-2
          Source Genetically modified E.coli
          Predicted Molecular Mass Dimer, 19.4/38.8 kDa (165/230 aa)
          AA Sequence MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPENHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
          Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
          Product Reconstitution Sterile water at 0.1 mg/mL
          Country of Origin USA

           

          Specification* Method of Determination Acceptance Criteria
          Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
          Endotoxin Kinetic LAL ≤ 0.1 EU/µg
          Biological Activity (ED50) HUVEC proliferation ≤ 10 ng/mL

           

          *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

          Specifications

          Storage
          At or below -20°C
          Shelf Life
          12 months from date of receipt when stored at -20°C to-80°C as supplied.
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