Recombinant Mouse IL-6

In stock

Catalog ID

200-02

Size	Stock	SKU	Unit Price
10 µg	In Stock	200-02-10UG	$176.00
10 µg (Animal-Free)	Inquire for Availability	200-02AF-10UG	$192.00
100 µg	In Stock	200-02-100UG	$567.00
100 µg (Animal-Free)	In Stock	200-02AF-100UG	$626.00
500 µg	In Stock	200-02-500UG	$1,895.00
500 µg (Animal-Free)	Inquire for Availability	200-02AF-500UG	$2,082.00
1 mg	In Stock	200-02-1MG	$3,158.00
1 mg (Animal-Free)	Inquire for Availability	200-02AF-1MG	$3,474.00

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Details

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune response upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions, is capable of promoting fever, and signals through the cell-surface type I cytokine receptor complex containing the IL-6Ra and gp130 chains. Human IL-6 is active on mouse and rat cells.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	IFN-β2, B-cell Differentiation Factor, BSF-2, HSF, MGI-2
Accession Number	P08505
Source	Genetically modified E.coli
Predicted Molecular Mass	Monomer, 21.9 kDa (188 aa)
AA Sequence	MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile 10 mM HCl at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	B9 cell proliferation	≤ 0.05 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to -80°C as supplied.

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