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Recombinant Mouse β-NGF

In stock
Catalog ID
200-11
Size Stock SKU Unit Price Qty
5 µg Inquire for Availability 200-11-5UG
$73.00
    20 µg In Stock 200-11-20UG
    $183.00
      100 µg In Stock 200-11-100UG
      $457.00
        500 µg Inquire for Availability 200-11-500UG
        $1,971.00
          1 mg Inquire for Availability 200-11-1MG
          $3,284.00
            5 µg (Animal-Free) In Stock 200-11AF-5UG
            $79.00
              20 µg (Animal-Free) Inquire for Availability 200-11AF-20UG
              $200.00
                100 µg (Animal-Free) Inquire for Availability 200-11AF-100UG
                $504.00
                  500 µg (Animal-Free) Inquire for Availability 200-11AF-500UG
                  $2,165.00
                    1 mg (Animal-Free) Inquire for Availability 200-11AF-1MG
                    $3,613.00
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                      Details

                      Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

                      Instructions

                      Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                      Technical Specifications

                      Alternate Names beta-NGF
                      Accession Number P01139
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Noncovalent homodimer, 13.6 kDa/27.2 kDa (121/242 aa)
                      AA Sequence MSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA

                       

                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) TF-1 cell proliferation ≤ 5 ng/mL

                       

                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      beta-NGF beta NGF

                      Specifications

                      Storage
                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to-80°C as supplied.
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