Recombinant Mouse β-NGF

In stock

Catalog ID

200-11

Size	Stock	SKU	Unit Price
5 µg	Inquire for Availability	200-11-5UG	$70.00
5 µg (Animal-Free)	In Stock	200-11AF-5UG	$76.00
20 µg	Inquire for Availability	200-11-20UG	$176.00
20 µg (Animal-Free)	Inquire for Availability	200-11AF-20UG	$192.00
100 µg	In Stock	200-11-100UG	$439.00
100 µg (Animal-Free)	In Stock	200-11AF-100UG	$485.00
500 µg	Inquire for Availability	200-11-500UG	$1,895.00
500 µg (Animal-Free)	Inquire for Availability	200-11AF-500UG	$2,082.00
1 mg	Inquire for Availability	200-11-1MG	$3,158.00
1 mg (Animal-Free)	Inquire for Availability	200-11AF-1MG	$3,474.00

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Details

Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

Technical Specifications

Alternate Names	beta-NGF
Accession Number	P01139
Source	Genetically modified E.coli
Predicted Molecular Mass	Noncovalent homodimer, 13.6 kDa/27.2 kDa (121/242 aa)
AA Sequence	MSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G
Formulation	Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution	Sterile water at 0.1 mg/mL
Country of Origin	USA

Specification*	Method of Determination	Acceptance Criteria
Purity	Reducing and Non-Reducing SDS PAGE	≥ 95%
Endotoxin	Kinetic LAL	≤ 0.1 EU/µg
Biological Activity (ED₅₀)	TF-1 cell proliferation	≤ 5 ng/mL

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA. The values provided here are minimum expected values to pass internal requirements.

Specifications

Storage

At or below -20°C

Shelf Life

12 months from date of receipt when stored at -20°C to-80°C as supplied.

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