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Recombinant Human TGF-α

In stock
Catalog ID
Size Stock SKU Unit Price Qty
25 µg In Stock 100-209-25UG
    100 µg Inquire for Availability 100-209-100UG
      250 µg Inquire for Availability 100-209-250UG
        500 µg Inquire for Availability 100-209-500UG
          1 mg Inquire for Availability 100-209-1MG
            25 µg (Animal-Free) In Stock 100-209AF-25UG
              100 µg (Animal-Free) In Stock 100-209AF-100UG
                250 µg (Animal-Free) In Stock 100-209AF-250UG
                  500 µg (Animal-Free) Inquire for Availability 100-209AF-500UG
                    1 mg (Animal-Free) Inquire for Availability 100-209AF-1MG

                      Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family. TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling. TGF-α functions as a mitogen to activate epithelial cell proliferation, growth, and differentiation. In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier’s disease. TGF-α is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells.

                      Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.


                      Centrifuge vial before opening.  Suspend the product by gently pipetting the above recommended solution down the sides of the vial.  DO NOT VORTEX.  Allow several minutes for complete reconstitution.  For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

                      Technical Specifications

                      Alternate Names TGF-alpha, EGF-like TGF, ETGF, TGFA, TGF type 1
                      Accession Number P01135
                      Source Genetically modified E.coli
                      Predicted Molecular Mass Monomer, 5.6 kDa (50 aa)
                      Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
                      Product Reconstitution Sterile water at 0.1 mg/mL
                      Country of Origin USA


                      Specification* Method of Determination Acceptance Criteria
                      Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
                      Endotoxin Kinetic LAL ≤ 0.1 EU/µg
                      Biological Activity (ED50) BALB/c 3T3 Cell Proliferation ≤ 2 ng/mL


                      *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

                      TGF-alpha TGF alpha


                      At or below -20°C
                      Shelf Life
                      12 months from date of receipt when stored at -20°C to -80°C as supplied.
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