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Recombinant Human RANTES / CCL5

In stock
Catalog ID
100-138
Size Stock SKU Unit Price Qty
5 µg In Stock 100-138-5UG
$73.00
    20 µg In Stock 100-138-20UG
    $183.00
      100 µg In Stock 100-138-100UG
      $457.00
        500 µg In Stock 100-138-500UG
        $1,971.00
          1 mg In Stock 100-138-1MG
          $3,284.00
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            Details

            Regulated upon activation, normal T cell expressed and secreted (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites.

            Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

            Instructions

            Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws.

            Technical Specifications

            Alternate Names CCL5
            Accession Number P13501
            Source Genetically modified E.coli
            Predicted Molecular Mass Monomer, 7.9 kDa (68 aa)
            AA Sequence SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
            Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
            Product Reconstitution Sterile water at 0.1 mg/mL
            Country of Origin USA

             

            Specification* Method of Determination Acceptance Criteria
            Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
            Endotoxin Kinetic LAL ≤ 0.1 EU/µg
            Biological Activity (ED50) THP-1 chemotaxis ≤ 250 ng/mL

             

            *Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

            Specifications

            Storage
            At or below -20°C
            Shelf Life
            12 months from date of receipt when stored at -20°C to -80°C as supplied.
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