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Recombinant Human / Mouse TGF-β 3

In stock
Catalog ID
800-11
Size Stock SKU Unit Price Qty
10 µg In Stock 800-11-10UG
$183.00
10 µg (Animal-Free) In Stock 800-11AF-10UG
$200.00
100 µg In Stock 800-11-100UG
$711.00
100 µg (Animal-Free) In Stock 800-11AF-100UG
$784.00
500 µg Inquire for Availability 800-11-500UG
$3,503.00
500 µg (Animal-Free) Inquire for Availability 800-11AF-500UG
$3,857.00
1 mg Inquire for Availability 800-11-1MG
$5,839.00
1 mg (Animal-Free) Inquire for Availability 800-11AF-1MG
$6,422.00
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Details

Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β2, and –β3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-β3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.

Product images on the website are not representative of actual product, including, but not limited to differences in cap color, tube type, or label format.

Instructions

Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution.

Technical Specifications

Alternate Names None
Accession Number P10600/P17125
Source Genetically modified E.coli
Predicted Molecular Mass Dimer, 12.9/25.7 kDa (113/226 aa)
AA Sequence MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
Formulation Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Product Reconstitution Sterile water at 0.1 mg/mL
Country of Origin USA

 

Specification* Method of Determination Acceptance Criteria
Purity Reducing and Non-Reducing SDS PAGE ≥ 95%
Endotoxin Kinetic LAL ≤ 0.1 EU/µg
Biological Activity (ED50) Inhibition of IL-4-induced HT-2 cell proliferation ≤ 1 ng/mL

 

*Lot-specific values for the above specifications are supplied with each product on its corresponding COA.  The values provided here are minimum expected values to pass internal requirements.

TGF beta TGF-beta

Specifications

Storage
At or below -20°C
Shelf Life
12 months from date of receipt when stored at -20°C to -80°C as supplied.
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